Top 7 e-Prescribing (eRx) & Pharmacy Software

eClinicalWorks is a cloud-based ambulatory EHR and practice management platform used by more than 180,000 physicians and nurse practitioners. It bundles clinical documentation, ePrescribing, a patient portal, and healow telehealth and patient engagement tools. Sunoh.ai adds an AI medical scribe, and a percentage-based RCM service is offered.

NextGen Healthcare sells ambulatory EHR, practice management, and revenue cycle software in two editions: NextGen Office for practices under 10 providers and NextGen Enterprise for larger groups. It supports 40+ specialties with 2,000+ clinical templates and includes ambient AI documentation, virtual visits, a patient portal, and Mirth interoperability tools.

DrChrono is a cloud-based EHR, practice management, and medical billing platform with native iPad and iPhone apps, now branded 'DrChrono by EverHealth.' It combines charting with speech-to-text, scheduling, eligibility checks, claims management, telehealth, and the OnPatient patient portal for practices ranging from solo providers to multi-location clinics.

SimplePractice is a cloud-based EHR and practice management platform for health and wellness practitioners, primarily therapists and other mental health clinicians, plus SLPs, OTs, and psychiatric prescribers. It combines scheduling, documentation templates, billing and insurance tools, telehealth, and a client portal, with published monthly plans starting at $49.

Elation Health is a cloud-based EHR built for primary care, including independent practices, direct primary care, and value-based care groups. It offers charting, ePrescribing, a patient portal (Patient Passport), and an optional integrated billing service, with add-ons for telehealth and Note Assist AI scribing. Per-provider pricing is published in the vendor's product guide.

Tebra is a cloud-based practice management and EHR platform for independent private practices, formed from the Kareo and PatientPop family. It combines scheduling, billing and claims, clinical charting, telehealth, patient engagement and practice marketing in one system, licensed per prescribing provider with non-clinical staff included.

Office Ally is a healthcare clearinghouse and practice software vendor whose Practice Mate practice management system is offered at $0, with transaction fees for some services. It pairs scheduling and billing with the Service Center all-payer claims portal and an optional EHR 24/7 module, and is aimed at small and mid-size practices.

VSee is a telehealth platform that ranges from a free plan for solo clinicians to white-label enterprise deployments. Its paid tiers add waiting rooms, scheduling, intake, payments, e-prescribing and RPM. It supports connected exam devices such as stethoscopes and otoscopes, and it holds a FedRAMP High ATO.