Who Hyro is best for
Hyro is a New York company founded in 2018 by Israel Krush and Rom Cohen, who started it in the Cornell Tech Startup Studio. It builds conversational AI agents for health system call centers. The agents answer patients on the phone, by text, in web chat and in mobile apps, and either finish routine tasks such as booking an appointment or refilling a prescription, or route the caller to the right person with context. Hyro says it works with about 45 large healthcare organizations, including Intermountain Health, Sutter Health, Baptist Health, Bon Secours Mercy Health and Hackensack Meridian Health.
Best for
- Health systems and hospital groups running a central patient access call center
- Organizations on Epic or Salesforce that want agents tied into existing workflows
- Contact centers on Cisco Webex or similar platforms that want AI routing in front of live agents
Not ideal for
- Solo and small independent practices without a contact center
- Practices looking for a published monthly price or quick self-serve setup
- Offices that mainly need after-hours on-call paging
Hyro pros and cons
Pros
- Handles scheduling, cancellations, rescheduling, refills, billing questions and provider search
- Agentic routing sends callers to the right department or live agent with context
- Works across phone, SMS, web chat and mobile apps
- Answers only from the organization's own approved content
- Large, named health system customers and published case studies
Cons
- No published pricing
- Designed for enterprise contact centers, not small practices
- Compliance details come mainly from press releases and partner listings rather than a public trust page
- Results such as reduced call abandonment are vendor-reported
Hyro pricing
As of November 2026, Hyro does not publish prices. Its Optum Marketplace listing directs buyers to request a demo or contact sales. Expect an enterprise quote based on your call volume, channels and integrations.
Key features
- Appointment management: patient identification, new patient registration, scheduling, confirmations, cancellations and rescheduling, following the organization's scheduling rules in the EMR
- Prescription refills and billing questions handled by voice or text
- Smart routing: routes, resolves or deflects calls within existing telephony workflows
- FAQ answers drawn from the organization's own knowledge base
- Provider and location search
- IT help desk tasks such as password resets by SMS
- Patient intelligence: analytics on trends, keywords and knowledge gaps from patient conversations
- 24/7 self-service by voice, chat and SMS
HIPAA, security and integrations
Hyro describes its AI agents as HIPAA compliant, and its Optum Marketplace listing says they draw only from the organization's own HIPAA-compliant content rather than outside sources. Coverage of its Sutter Health deployment says the rollout was set up to comply with HIPAA and SOC 2 requirements. Hyro's own site was not reachable for us, so ask for its BAA and SOC 2 report directly.
Hyro connects to EHRs, scheduling and billing systems. Press coverage cites interoperability with Epic and Salesforce, and its Optum Marketplace listing mentions athenahealth. For contact centers, it integrates with Cisco Webex Contact Center and Cisco Finesse and embeds into existing telephony workflows.
Hyro alternatives
- Assort Health — voice AI for specialty and primary care groups with direct Epic, athenahealth and NextGen scheduling.
- Keona Health — patient access CRM for contact centers, with an AI voice agent and nurse triage protocols.
- Hello Patient — AI agents for calls, texts and chat aimed at multi-location groups.
- Lydoh — flat-priced AI phone assistant for small practices.
- Salesforce Health Cloud — CRM for health systems that want patient access workflows in Salesforce.



